Carbomer uses It shows quick dispersion, no neutralizing phase, constant pH during the production process. Carbomers are polymers that have the ability to absorb and retain large amounts of water, resulting in a gel-like consistency. Vidisic ® is a clear sterile gel and is supplied in a plastic/aluminium tube. Carbopol ® * is a water soluble polymer, used as an emulsifying, stabilising, suspending, thickening in many industries and is also used as gelling agent in hand sanitizer gels and other products. Intermediate drug release can be achieved by combining Carbopol 971P NF and 974P NF polymers – Figure 3. The Carbomers are white, fluffy powders frequently used as gels in cosmetics and personal care products. Secure . Many other Iron-containing products been successfully used in over-the-counter and pharmaceutical formulations to impart rheology modification, mucoadhesion, controlled drug release, and many other unique properties. Topical Applications - All polymers listed in the chart below are suitable for use in topical applications and are present in commercialized Carbopol ® 971P NF Carbomer 940 is a versatile component that is frequently used in skincare products due to its thickening, stabilising, and emulsifying qualities. Carbopol 71G NF is the only granular carbomer available for direct compression formulations, providing increased versatility in the manufacture of oral solid dose products Benefits of Polybutene for Skin . Methods: Sixty-five subjects with dry eye were recruited and supplied with eyedrops containing either Carbomer or SH to use for a month. Purchasing and Storing PAA. It is a common ingredient in formulations used for both industrial and consumer products. Louis, MO, USA), 2 mM L-glutamine (G7513, Merck, Darmstadt, Germany), 100 µg/mL penicillin-streptomycin (V900929, Merck) were added to 24 In other studies using the same procedure, the ocular irritation potential of acrylates/C10-30 alkyl acrylate cross polymer (as Carbopol Ultrez 20 and Carbopol Ultrez 21) was evaluated using groups of 3 rabbits. At this point the Carbomer turns into a Carbopol 934P was used as a gelling agent, with two permeation enhancers, i. Carbopols, hydrophilic polyanionic carbomers, are polymers of acrylic acid cross-linked with polyalkenyl ethers or divinyl glycol. Sucrose esters are frequently used surfactant This robust formulation of Cetearyl alcohol can operate effectively across a diverse range of temperatures, making it beneficial for use in personal care products. 2% EYE GEL (carbomer) Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines. 6,00376 Poly(caprolactone) [24980-41-4] Mw ~45,000 Discover Versatility of Carbomer Powder in Skin Care. The carbomers are white, fluffy powders but are frequently used as gels in cosmetics and personal care products. Here, we may understand the beneficial effects products provide to skin with daily uses. This website offers a large selection of cosmetic Information About Carbomer Uses of Carbomer. Holds ingredients together: Polybutene is often used as a binding agent, says Dr. Found in various forms like carbomer 934 and carbomer 940, they are applied topically on the skin to help products spread evenly. In this article, we discuss “Carbomer 940 vs Carbomer Homopolymer” by precisely contrasting their Carbomer eye gels are used to relieve eye dryness and soreness. PNC 400 These cells were randomly divided into control group, carbomer group, and VAP group, VAP gel and carbomer gel were added into VAP and carbomer group respectively, then fetal bovine serum (FBS, 10%, F8318, Sigma-Aldrich, St. Rabbits showed minimal skin ir- ritation and zero to moderate eye irritation when tested with Carbomers-910 and -934. 2% contains the active ingredient, carbomer. Viscotears is used to make your eyes more comfortable when they feel dry. Carbomer eye gel Carbomer: Carbomer: Authorised use: Excipient: Excipient: Definitions: specified: specified: Identification: specified: Infra red spectrum Dispersion at pH 7. Note on toxicity testing: The toxicity of carbomers has been summarized by the Cosmetic Ingredient Review Expert Panel in their assessment of the safety of the carbomers for cosmetic When preparing carbomer-thickened formulations, care must be taken to ensure uniform dispersion of the carbomer in order to avoid grainy textures and the formation of “fish eyes,” i. The immediate implementation While polymers have been used in ocular drug delivery for decades, with the first polymer intravitreal implants receiving approval in 1996 and topical applications making use of them since the 1970s, many applications of polymers in ocular Being an anionic binder, carbomer cannot be used with a divalent alkaline drug, in case of the presence of precipitation [77]. In Dec. Additional information. used nanoporous silica as a drug carrier and mixed nanoporous silica with CsA to prepare CsA-eluting CLs using supercritical fluid technology, and the CLs could release CsA continuously for 48 h, exhibiting good eye penetration, improving the clinical parameters and conjunctival goblet cell density, and reducing the number of inflammatory cytokines. Carbomer Uses in Everyday Skin Routine. There are only preliminary studies on the clinical use of glass carbomer thus far; however, no long-term studies have been conducted for this material. Carbomer is a synthetic polymer that is derived from acrylic acid. View Carbomer’s uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg. Children and adolescents aged to 18 years In 2019, the Expert Panel reviewed 126 acrylates copolymers, including carbomer, and found them safe in cosmetics in the present practices of use and concentration. Carbomer DrugBank Accession Number DB15649 Background. Things to consider before you start to use Carbomer 3. Show For Liquivisc® 0. Their properties are utilized to control release as well as to improve biologic Carbomer plays a significant role in the formulation of skin care products, contributing to their texture, stability, and overall effectiveness. , partially hydrated agglomerates of carbomer particles that fail to completely disperse. Esters . a. Carbomer 974P is a carbomer that is the major non-aqueous component (5% polymer, 94% water) of a proprietary formulation called BufferGel, which also contains dibasic potassium phosphate, magnesium sulfate, dibasic sodium phosphate, sorbic acid, monobasic sodium phosphate, and disodium EDTA. (858) 552-0992; sales@carbomer. 1g contains 2mg carbomer, water for injections, cetrimide, sorbitol, sodium hydroxide. The molecular weight of carbomer is estimated to be at 7×10 5 to 4×10 9 Da. Viscotears should always be the last eye drops used. Currently, there are only a few polymeric rheology modifiers capable of adequately structuring anhydrous toothpastes. Viscotears contains 2. Further information 1. Safety Assessment and FDA Approval. Being an anionic binder, carbomer cannot be used with a divalent alkaline drug, in case of the presence of precipitation [77]. Carbopol ® polymers 1P N thyl Acetate Carbomer Homopolymer ype A Carbomers Carboxyvinyl Polymer Carbomer Homopolymer •-•, 11, P N thyl Acetate Carbomer Homopolymer ype B Carbomers Carboxyvinyl Polymer Carbomer Homopolymer • • • 2, , N Cosolvent2 Carbomer Homopolymer ype C Carbomers Carboxyvinyl Polymer Carbomer Homopolymer Carbomer// Carbomer DMF, CEP, Written Confirmations, FDF, Prices, Patents, Patents & Exclusivities, Dossier, Manufacturer, Licensing, Distributer, Suppliers, News FEATURES AND BENEFITS. Carbomers, also known as Rheology Modifiers, are used to optimize cosmetic & pharmaceutical product formulations in profound ways. Carbomer (crosslinked polyacrylic acid (CPA)) is widely used to structure anhydrous toothpastes but its viscoelastic properties in the absence of water are poor and The use of Carbopol and its advantages in the mucoadhesive topical application has gained considerable interest with several published studies and is available in various grades. • Increasing the usage level of Carbopol tends to result in slower and more linear drug release. 5% depending on the type of formulation desired viscosity. gov A . Contact. Identification Summary. It is also used to study solute diffusion in polyvinyl alcohol/polyacrylic acid copolymer hydrogel. The blood TS concentration profile was similar to the circadian one. Recent Posts. 045-0. How Carbomer Works. Ocular lubricants should be prescribed by BRAND where stated to ensure the most cost-effective If a patient needs to use carbomer more frequently than 3 times a day, a more viscous lubricating eye drop Amneal said that it uses carbomers “from the world’s largest and most trusted manufacturer that also supplies for most branded products, and incoming materials undergo regular quality testing. How to store Carbomer 6. 51) are synthetic high-molecular-weight polyacrylic acids cross-linked with allyl sucrose or allyl pentaerythritol and contain between 56 and 68% w/w carboxylic acid groups. Carbomers are acid-based polymers capable of Carbomer is a term used for a series of polymers primarily made from acrylic acid. Key Features & Benefits . Increasing the pH to >6. Things to consider before you start to use Viscotears DO NOT use Viscotears if: • If you are allergic to carbomer or any of the Carbomer is a high molecular weight polymer compound used commonly in the cosmetic industry. gov website belongs to an official government organization in the United States. What is a Carbomer. 6 In addition to the ingredients that have been previously reviewed by the Panel, an additional 70 acrylates copolymers that Triethanolamine is used primarily in making surfactants, such as for emulsifier. Neutralization can be carried out with inorganic bases such as NaOH or KOH or triethanolamine (TEA). It offers high viscosity and clarity. • DOW Versene 100 (Tetrasodium EDTA): Generally, you would add 1 part Tetrasodium EDTA to 1 part Carbomer 940. Carbomers are white, fluffy powders but are frequently used as gels in cosmetics and personal Carbomer is a polymer that is commonly used as a thickening agent, stabilizer, and emulsifier in skin care formulations. 2% is used to make your eyes more comfortable when they feel dry. Your Carbopol 934P NF polymer can be used to formulate gels, emulsions and suspensions. but found suddenly lost its viscosity which allready i made with sodium chloride. Based on its official functions listed in the Carbomer is a high molecular weight polymer compound used commonly in the cosmetic industry. 2% DO NOT use Carbomer 980 0. Carbomer (Carbopol ®*) is a water-soluble polymer valued for its emulsifying, suspending, stabilizing, and thickening properties. Carbomer is a type of ophthalmic lubricant. They are also used as artificial tears. It even provides anti-aging benefit in a gel formula. The everyday encounter with carbomer may only happen with different skincare products. ’s offers Polycaprolactones with various molecular weights ranging from 400 to 80,000 Daltons. Carbomer is a thickening agent that helps improve the texture of the products and also binds the other ingredients together - preventing them from separating. This makes it easier for manufacturers to suspend heavy particulates in a recipe. Cyclohexane is mainly used for the industrial production of adipic acid and caprolactam, which are precursors to nylon. It is Carbopol® 940 polymer is a white powder, crosslinked polyacrylic acid polymer. 2023, the US FDA released guidance on benzene-grade carbomer formulations, which triggered pharmaceutical manufacturers to assess risk, test finished products, and reformulate drug products with benzene-grade carbomer. The Carbomer polymers are used in cosmetics and emulsifying agents at concentrations up to 50%. Carbomer 940 is a gelling agent. com; Contact Us. Sixty-one patients with symptoms and signs of dry eyes were treated with each preparation separately for two weeks in a multicentre, randomi Purpose: This randomized, double-masked study compared the effectiveness of two commercially available ocular lubricants containing either 0. Uses. The Carbopol-based gel was used as a vehicle for transferosomes loaded with 5-FU , paclitaxel , methotrexate , tofacitinib , tamoxifen citrate , and others. because it is inversely proportional to the thickness of . To inquire more, Contact Us . A popular use of docusate sodium is found in laxatives or stool softeners used to influence the muscles in the lower abdomen to produce the movement of the bowels. Carbomer’s Cosmetic Uses. Each tube contains 10 g of Viscotears. What Carbomer 980 0. This blog discusses Carbomer 940, its benefits, and how it is utilised in skincare Carbomer is used in the treatment of Dry eyes. Carbopol® ETD 2623 polymer: Carbopol® ETD 2623 polymer is a hydrophobically-modified, easy-to-disperse, moderately crosslinked polyacrylic acid polymer powder polymerized in a toxicologically-preferred cosolvent system. Carbomer 35,000 (Carbopol® 974P) can be used on skin and mucous membranes). 5% by wt water and 0. Wong et al. Carbomer eye gels are used to relieve eye dryness and soreness. NHS medicines information on carmellose sodium eye drops – what they're used for, side effects, dosage and who can use them. How often can you use it: As long as it's delivered from a standard cosmetic product and does not cause irritation, products with triethanolamine are considered safe to use Carbomer is a high molecular weight polymer compound used commonly in the cosmetic industry. Carbomers are acid-based polymers capable of strong mucoadhesion, particularly at low pH values. Generic Name Carbopol 974P DrugBank Accession Number DB05384 Background. How to use Carbomer 4. 5: 60 to 95 (according to neutralizer) 5 to 9: low: CARBOPOL 980 (Lubrizol) ASHLAND 980 Carbomer (Ashland). EasyDisperse™It can be inflated easily and quickly in the water. Traditional Carbomers may contain trace amounts of benzene, a When carbomer is used as an emulsifier, an inorganic alkali neutralizer and an organic alkali neutralizer can be used for double neutralization. Carbopol® Silk 100 polymer is a crosslinked polyacrylic acid that is polymerized in a toxicologically-preferred cosolvent system. Different numbers of Carbomer 940, Carbomer 934, Carbomer 1342, and Carbomer 941 as solvents will be required to reformulate to avoid use of these carbomers in their drug products once the USP monographs have been Identification Summary. They have a high molecular weight and swell in aqueous solutions, which enables Carbomer’s Cosmetic Uses. If you are using other eye drop or eye ointment medicines, wait at least 5 minutes between each medicine. com/Life-Sciences for more information 1. com/Life-Sciences for more information Download Citation | Carbomers and their use in pharmaceutical technology | Carbomers, high-molecular polymers based on acrylic acid, are employed in the technology of drugs as auxiliary substances Acrylic acid is commercially available in USA in 2 grades: (a) technical grade for esterification and polymerization, and (b) glacial grade for production of water-sol resins. Manufacturer: The inactive ingredients in VOLTAREN® GEL include: carbomer homopolymer Type C, cocoyl caprylocaprate, fragrance, isopropyl alcohol, mineral oil, polyoxyl 20 cetostearyl ether, propylene glycol, purified water, and strong ammonia solution. Uses for Voltaren Gel. Meanwhile, the spreadability increases . Carbomer 940, Composition, Properties, uses and Carbomer Ratio : Learn about Carbomer 940 in full details, and its ratio into a mixture. 7. Hirsch, allowing the cohesion of different cosmetic ingredients within a single formula. Carbomers readily absorb water, get hydrated and swell. , propylene glycol (PG) and oleic acid (OA), which were selected as variables X1 and X2, respectively. lubrizol. Pullulan is a versatile polysaccharide known for its role in food preservation, pharmaceuticals, and environmentally friendly packaging. Carbomero. It is available on prescription or you can buy it without a Carbomer is a term used for a series of polymers primarily made from acrylic acid. 1-0. Vagisil should only be used externally, especially on the skin just outside of the vagina and around the anus by adults and children older than 12 years. com/Life-Sciences for more information Sodium carbomer is a blend of sodium and gelling agent carbomer. For example, you might come across terms such as “Carbomer 940” or “Carbomer 980” on Carbomer is a key ingredient in many personal care products, serving as a thickener and stabilizer to enhance the texture of creams, gels, and lotions. What you need to know before you use Liposic ® Eye Gel Do not use Liposic ® Eye Gel: - if you are allergic to Carbomer or any of the other ingredients of this medicine (listed in section 6). 9% Carbomer 940 and 1% Suttocide A will 1. Each tube Viscotears contains the active ingredient, carbomer (polyacrylic acid). 5%) Synthalen K Carbomer 5-11 0,1 –1,5% 40000 60000 Synthalen L Carbomer 5-11 0,1 –1,5% 6000 9000 Synthalen M Carbomer 5-11 0,1 –1,5% 30000 40000 Synthalen E80 Carbomer 5 - 11 0,1 –1,5% 40000 60000 Synthalen E83 Carbomer 5 - 10 0,1 –1,5% 20000 42000 Easygel DO Carbomer 5 - 12 0,1 –1,5% 45000 65000 Long sessions of reading, TV watching, and computer use reduce blink rate and exacerbate the problem. In this guide, we dive into the specifics of “what is Carbomer”, its View carbomers information, including dose, uses. gov websites use HTTPS Carbomer: CARBOPOL ULTREZ 10 (Lubrizol) 0. Check the label thoroughly before using Vagisil. 1, 2025. Carbomer is ideal for Thickening & Enhancing texture of Cosmetic products like Creams, Lotions & Serums. By using the emulsification solvent evaporation method, floating microspheres can also be prepared with different grades of Carbopol: Carbopol 934, Carbopol 910, Carbopol 940, and Carbopol 941. 44,45 The test material was evaluated undiluted and as a 5% dilution in distilled water. The Cosmetic Ingredient Review (CIR) has declared Cetyl alcohol as safe for use in cosmetics. It is one of a group of eye drops called ‘artificial tears’. However, there is a far broader reach to docusate sodium’s usefulness and place in consumer products. It is also employed as a thickening, suspending, emulsifying and dispersing agent in pharmaceuticals, cosmetics, adhesives and Carbomer is a term used for a series of polymers primarily made from acrylic acid. 5%) Synthalen K Carbomer 5-11 0,1 –1,5% 40000 60000 Synthalen L Carbomer 5-11 0,1 –1,5% 6000 9000 Synthalen M Carbomer 5-11 0,1 –1,5% 30000 40000 Synthalen E80 Carbomer 5 - 11 0,1 –1,5% 40000 60000 Synthalen E83 Carbomer 5 - 10 0,1 –1,5% 20000 42000 Easygel DO Carbomer 5 - 12 0,1 –1,5% 45000 65000 Cyclohexane is a cycloalkane with the molecular formula C 6 H 12. The undiluted test material produced moderate Choi et al. Understanding Polyacrylic acid (PAA). Side Effects of They performed the study on a Caucasian male model with reduced blood testosterone levels. Learn how to use Carbomer Powder in Skin Care routines & enjoy Smoother, Glowing Skin. PNC 400 shares the advantageous features of a 940 type carbomer but demonstrates significantly more efficient dispersion. Polyacrylic acid is used in disposable diapers and in ion exchange resins. How often should you use? Instill 1 drop into conjunctival sac 3 to 5 times or more frequently, during day and before retiring for night. Hypromellose, or hydroxypropyl methylcellulose (HPMC) 8, is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. Plus, Carbomer 940 is also useful to use to develop a suspension in a formula. Let’s explore the specific functions and benefits of carbomer in skin care in more detail. This article explores the Pullulan benefits, function, and uses, highlighting why it is sought after in various industries, particularly for its unique Pullulan benefits, function and uses. 1 to 0. Carbomer, also known as Acrylic Acid Polymer, Acrysol, and Carbopol 940, is widely used to build viscosity and control the consistency and flow of cosmetic products. A total number Sodium Carbomer. Triethanolammonium salts in some cases are more The present invention is directed to dispensers, dispenser components and related methods for reducing or preventing sticking, drying, buildup, clogging, and/or misdirection of carbomer gel based products such as hand sanitizers by incorporating one or more salts, such as sodium chloride, as an additive to the polymer used to make certain pump and nozzle components of Cancer has been an enormous pain point for patients and regulatory bodies across the globe. Ingredients. They are acrylic polymers. PATIENT INFORMATION LEAFLET Pregnancy and breast-feeding Anhydrous toothpaste formulations are used to protect water-sensitive active ingredients. ” Acrylates Crosspolymer: A versatile polymer used in various formulations, providing superior texture and stability. without using heat But must use alkaline (eg. It comes in the form of white Carbomer, also known as Acrylic Acid Polymer, Acrysol, and Carbopol 940, is widely used to build viscosity and control the consistency and flow of cosmetic products. The type that is sold is a special grade. Ethanol has been replaced by propylene glycol in most Official websites use . Carbomer must be thoroughly mixed and hydrated. It is suitable for formulating clear viscous gels. Thanks to the affordability of Carbomer 940, many cosmetic manufacturers are using Carbomer 940 because of it’s gelling, thickening, and suspending properties. Uses of PAA. Who should use it: In general, anyone who does not have an allergy to it. The carbomer neutralized by the inorganic alkali is soluble in the water phase, Carbomer. Presentation. This makes it an ideal ingredient Carbomer is a term used for a series of polymers primarily made from acrylic acid. Our biomedical grade products category includes docusate sodium which comes in a compounded powder form from docusate sodium USP and sodium benzoate NF with purity of 83-87%. compared the adhesion properties of carbomer, sodium carboxymethylcellulose (CMC-Na) and HPMC. Cyclohexane is a colourless, flammable liquid with a distinctive detergent-like odor, reminiscent of cleaning products (in which it is sometimes used). • Suttocide A: Generally, you would use slightly more Suttocide A than Carbomer 940, for instance 0. The FDA’s notice states that: Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist have told you. The combination of vitamin A and carbomer can increase the stability Typical use level 0. Carbomer uses are smooth on spreadable products that boost consumer satisfaction due to its remarkable thickening and suspending capabilities. Benefits of Using Carbomer 940. It also enhances & utilize penetration/effectiveness of key actives. What Carbomer is and what it’s used for Carbomer contains the active ingredient, carbomer (polyacrylic acid). Most Carbopol polymers are high molecular weight acrylic acid chains usually crosslinked, and are available as powders or liquids. Additionally, Carbopol 974P NF polymer can be used to formulate viscous gels, emulsions and suspensions. PNC 400 by 3V Sigma is a pre-neutralized polyacrylate that can be used as rheology modifier, thickener, stabilizer and suspending agent. are made using a v ariety of polymers, including Carbomer 940, sodium carboxymethylcellulose, chitosan and other ingredients such as ethanol, lav ender oil, and propylene gl ycol, methylparaben 2. These compounds can absorb large amounts of water, increasing in volume recommended range of carbopol use as gelling agent (0. They're commonly used in creams and lotions to enhance texture and stability. Not Available. e. Acrypol® 974P finds application in formulating styling products, shampoos and skin In November of 2022, the Complex Excipients Expert Committee (EC) posted notice that it intends to omit the USP-NF monographs for Carbomer 934, Carbomer 934P, Carbomer 940, Carbomer 941, and Carbomer 1342, with a targeted official date of Aug. It is a white, fluffy powder that is highly absorbent and can hold up to 100 times its weight in water. 1% and 0. Subchronic feeding of rats and dogs with Carbomers in skincare are synthetic substances, originating from the family of acrylic acid polymers. Typical commercial glacial acrylic acid contains 98. You may need to read it again. 25% eye gel CarboMer Iron Dextran, with SKU 2-08543 and CAS number 9004-66-4, is available as a solid as well as an injectable solution ranging from small research amounts to bulk commercial quantities. Viscosity. Benzene Free Carbomer: Safety First What is Benzene Free Carbomer? Benzene free Carbomer is an innovative product designed to meet the safety concerns of formulators. 8 phosphate buffer was slower in the case of wet granulated tablets with 10% Carbopol ® 971P NF polymer than The Carbomer polymers are used in cosmetics and emulsifying agents at concentrations up to 50%. A hydrogel (Carbopol 980) based on ATD™ was used as a TS carrier, which influenced faster testosterone absorption, according to first-order kinetics. 2% is and what it's used for Carbomer 980 0. CARBOMER 0. Carbopols have found use in a diverse range of pharmaceutical What is a Carbomer (Carbopol ®) and how is it used?. Carbomer uses widely vary due to their ability to thicken, stabilize, and suspend formulations. 2. Blog. The type of carbomer used in a product may be indicated on the label, providing more information about the specific variant of carbomer being used. With allergies to Carbomer being rare, it can be used safely and effectively by almost anyone, ensuring a smooth, consistent texture without causing irritation. 4. It stabilizes various emulsions and produces wide range of flow & viscosities. These compounds can absorb large amounts of water, increasing in volume up to 1,000 times to form gels and thick solutions that are stable and resistant to spoilage. Improves Product Stability: When used in shampoos and body washes, Carbopol Polymer helps to suspend and stabilize It is a highly crosslinked powdered Carbopol polymer and provides very low viscosity at use levels less than 0. Cyclohexane is non-polar. An interesting study was presented by Shamim et al. 0, gives a gel structure. ) Carbomer 50,000 (Carbopol®980) is an easily spreadable gel for cutaneous application. Adult Apply 3–4 times a day, alternatively apply as required. Although not a "natural" product, Carbomer has no documented safety Carbomer is use to create gel-textured skin care formulas. 2% preparation) for carbomers To the eye. This rheology modifier and stabilizer also provides electrolyte International Cosmetic Ingredient Dictionary and Handbook (wINCI; Dictionary) as technical names for one ingredient, Carbomer. It delivers excellent suspending capability and stabilizes insoluble conditioning agents commonly used in 2-in Lightly crosslinked polymers, such as Carbopol ® 971P NF polymer, tend to be more efficient in controlling drug release than highly crosslinked polymers such Carbopol ® 974P NF polymer. Description: White, fluffy hygroscopic powders, swelling in water and other polar solvents: White, fluffy hygroscopic powders, swelling in Carbomer, Carbopol. 5-2%) [6]. Type of ingredient: Emulsifier and pH adjuster Main benefits: Stabilizes, balances a product's pH, and thickens the formula. Of this solution, you would generally use 2 parts KOH to every 1 part Carbomer 940. 5. Clarity Use Levels Viscosity Range (0. It is an extremely efficient rheology modifier capable of providing high viscosity and forms sparkling clear gels or hydro-alcoholic gels and creams. Confirm with the doctor if not sure about how to use Vagisil. 2% if: CarboMer is a Pharmecutical Chemicial Supplier and provider of docusate sodium. The New FDA Guidance. 2% and very high viscosity at use levels over 0. Carbomers can be found in a wide variety of product types including skin, hair, nail, and makeup products, as well as dentifrices. Carbopol is available in several than highly crosslinked Carbopol polymers (974P NF). Warnings and precautions Talk to your doctor or pharmacist before using Liposic ® Eye Gel. Possible side effects 5. 0% by wt acrylic acid, max of 0. Dosage. Carbomer is primarily used in skin care products as a thickening agent. Carbomer, Inc. 4% polyvinyl alcohol-based (PVA) offificial tear preparation. Rabbits showed minimal skin ir- ritation and zero to moderate eye irritation when tested with Carbomers-910 PNC 400 is a synthetic polymer pre-neutralized for ease of use, serving as a versatile thickener, suspending agent, and stabilizer in various cosmetic products. Carbomer has carved out a unique place in the realm of cosmetics, thanks to its diverse functionality. Since then, a number of extended release tablet formulations, which involve carbomer matrices, have been patented3. Consequently, the durability of this material in the oral cavity of patients is not yet known. The Carbomers are white, fluffy powders but are frequently used as gels in cosmetics and personal care products. This makes it an ideal ingredient for Carbopol® Silk 100 polymer is a crosslinked polyacrylic acid that is polymerized in a toxicologically-preferred cosolvent system. It is a key thickening ingredient, widely Also available in a drop form for daytime use. com/Life-Sciences for more information Carbopol® Aqua CC polymer is registered with EPA Inert ingredients as a nonfood use inert ingredient. Polysaccharide Iron Complex Specialty Products Carbopol Ultrez polymers provide self-wetting capabilities for polymer dispersion that does not require mixing, enabling greater ease of use in formulating and processing. Carbomer is a generic name used to describe a family of polymers that are crosslinked with a poly alkenyl ether. The gel produces a fine transparent film on your eye. 3% Carbomer 934 or 0. Home; Get timely information about what’s new and what’s coming up on the CarboMer blog. Used in combination to treat: Dry eyes: Combination Product in combination with: Cetrimonium (DB01718) Selecting between Carbomer 940 and Carbomer homopolymer can be critical for your product’s performance. How to Integrate Carbomer in Your Daily Skincare Regimen Carbomers, high-molecular polymers based on acrylic acid, are employed in the technology of drugs as auxiliary substances acting as emulsifiers, gel-forming substances, stabilizers of suspensions, and binders in tablets. These crosslinks give carbomer its unique properties of high viscosity and excellent thixotropic nature. Acrypol® 974P by Corel Pharma Chem acts as an emulsifier, thickener and stabilizer. Carbomer once fully hydrated is neutralised with Sodium hydroxide to bring the pH to 6 or greater. You can find carbomer in cosmetics such as shower gels, shampoos, conditioners, lotions, creams, Please read this leaflet carefully before you start to use Viscotears. It delivers excellent suspending capability and stabilizes insoluble conditioning agents commonly used in 2-in Most ingredients were originally intended for other uses and found their way into Cosmetic Use, however Carbomer was always formulated for Cosmetic Use. Type Small Molecule Groups Experimental Synonyms. 17 Dispersion of traditional carbomers usually requires that the Carbopol® Ultrez 20 polymer is a white powder, hydrophobically-modified cross-linked acrylate copolymer. Carbomer is used to make your eyes more comfortable when they feel dry. gov Carbomer, as a substrate of vitamin A, can form a liquid reservoir inside the gel after acting on the ocular surface. The carbomer in Liposic ® Eye Gel increases the thickness of the gel, which assists the gel in remaining in contact with the eye for a longer period of time. com. Medicinal forms and pricing. Child Apply 3–4 times a day, alternatively apply as required. Support: (866) 599-7896. Learn more. the g el preparation [20]. It is one of a group of eye drops called 'artificial tears'. Orange colour with Thymol Blue. Handwash Liquid, Form Dispersion Techniques with Carbopol® Polymers visit https://www. It is also an effective emulsifier. ’S POLYCAPROLACTONE PRODUCTS. Carbomers, Dry eyes including keratoconjunctivitis sicca, unstable tear film (using 0. Carbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of A granular carbomer is also available (Carbopol 71G). It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of Carbomer is usually used between 0. Carbomer is used in many skincare products, such as moisturizers, sunscreens, and anti-aging creams, to improve their texture and stability. Learn more at Paula’s Choice. kindly advise me when i can add carbopol while making my products using sles,CDEA,CAPB Its Uses, Properties, Applications. It is a white, fluffy powder that has the ability to absorb and retain water, making it ideal for products that aim to Carbomers, also known as Rheology Modifiers, are used to optimize cosmetic & pharmaceutical product formulations in profound ways. This announcement stems from multiple studies, where Carbomer is mainly used for skin, hair, nail, and dental treatment. The triethanolamine neutralizes fatty acids, adjusts and buffers the pH, and solubilizes oils and other ingredients that are not completely soluble in water. This protects, soothes and lubricates the surface of your eye and makes it feel more comfortable. Thickening, Suspending and Emulsifying with Carbopol Polymers visit https://www. Triethanolamine or Sodium Hydroxide or AMP (2-Amino-2-methyl-1-propanol)) in gelling . In this article, we discuss “Carbomer 940 vs Carbomer Homopolymer” by precisely contrasting their chemical structures and functional capacities, offering practical insights for their optimal use in various applications. It’s used as a film-forming agent in skin care products. Carbomer must be thoroughly mixed or hydrated before use, otherwise it will not work properly and has the risk of formation of lumps in the final formulation. Carbomer is commonly used to treat keratoconjunctivitis sicca and unstable tear film. Carbopol 971P NF, as well as all oral-grade Carbopol polymers, is solely polymerized in ethyl acetate, which is a toxicologically preferred class III solvent. Highly viscous, clear gel for mild to severe dry eyes Only gel that replicates all three layers of the tear film Carbomer 980, Cetrimide, Sorbitol, Medium-chain triglycerides, sodium hydroxide (for pH adjustment), purified water. In this study, a Generic Name Hypromellose DrugBank Accession Number DB11075 Background. Versatile Application: Carbopol Polymer (Ultrez 20) is a highly efficient thickening agent known for its versatility across a wide range of personal care formulations, including skin care, hair care, and body care products. Based on its official functions listed in the CosIng database, here are the key ways Carbomer earns its place in your beauty products: Emulsion Stabilising: Carbomer acts as the peacekeeper in your cosmetic Carbopol® 974P NF polymer was introduced for use in oral and mucosal contact applications such as oral liquids, bioadhesive formulations, oral care formulations and extended release tablets. Carbopol 974P is a polymer used as a lacrimal substitute to treat symptoms associated with dry eyes. Why Carbomer is Used in Skin Care. Apply the cream to the affected area three to four times daily for up to one week. Best known for its use in the cosmetic industry, it also has practical applications in medicine and hygiene. 055 mg/kg (ppm) of inhibitor CARBOMER, INC. • At low usage levels, due to the crosslinked nature, Sir, presently i am using sodium chloride to thicken my dish washing liquid and hand washes. Acute oral animal studies showed that Carbomers-910, -934, -934P, -940, and -941 have low toxicities when ingested. For external use only. Carbopol is utilized in a wide variety of cosmetic and personal care products, pharmaceuticals and household cleaners. Carbomers (Fig. Carbomers are frequently used in tear substitutes. The results presented that carbomer showed the highest adhesion, followed by CMC-Na and HPMC [78]. . 5. Official websites use . It is a polymer that is able to maintain moisture on the corneal surface for a longer period of time with less frequent application. Increases viscosity: Both doctors are quick to point out polybutene's chief function as a non-aqueous thickening agent, meaning it thickens formulas by targeting oils Moreover, Carbomer’s non-irritating nature makes it particularly beneficial for those with sensitive skin. 0 mg/g of the active ingredient, carbomer (polyacrylic acid). Carbomer; Carbomer homopolymer, unspecified type; Carbomere. Lubrizol’s benzene polymerized polymers do not meet the European Pharmacopeial “Carbomers” monograph because the residual benzene levels exceed the 2 ppm limit stipulated in the monograph. , which includes carvedilol in transferosomes for topical administration to prevent UV-induced skin cancer [ 146 ]. Carbomers are also suitable, for example, for the production of adhesive gels in the mucous membrane area. CarboMer, Inc. Carbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of Dispersion Techniques with Carbopol® Polymers visit https://www. Things to consider before you start to use Carbomer 980 0. It can continuously release moisture in the blink process, so as to better wet the eyes and increase the stability of tear film. Carbomer might be present in some eye gel to offer hydration. Careers. For example, as Theophylline release in pH=6. Its short flow, non-drip properties are ideal for applications such as clear gels, hydroalcholic gels, and creams. Carbomer 980 0. In the cosmetic industry, Carbopol is used as a thickener in lotions, creams and gels. 5%. The liquid gel also contains the inactive ingredients cetrimide (as a preservative), sorbitol, sodium hydroxide and water. Carbomer eye gel is quite runny and works like a liquid eye drop. - Keep this leaflet. 5 In 2003, the Panel reaffirmed that Carbomer is safe as used. Carbopol Ultrez 20 polymer is exceptionally easy to use as it self-wets and disperses within minutes. Dispersion Techniques with Carbopol® Polymers visit https://www. There can be variation in the licensing of different medicines containing the same drug. for more thickening i brought carbopol 940 and made a 5% gel with it and added it in my products. It is The efficacy and safety of a new carbomer containing ocular gel was compared to a commonly used 1. Exploring Carbomer Characteristics: Features and Benefits of Different Types. As three-dimensionally cross-linked microgels, carbomers do not dissolve but swell to a remarkable extent in water Selecting between Carbomer 940 and Carbomer homopolymer can be critical for your product’s performance. It exhibits short flow properties and a creamy sensory profile, and is therefore well suited for use as carbomer (polyacrylic acid) thickener, emulsion stabilising, film former (2) carvone: fragrance: Usage of ethanol in mouthwashes is very controversial and currently there are not many individual mouthwash products containing this solvent, but they are very popular and time-honoured. It is a water soluble, cross-linked and high molecular weight polymer of acrylic acid. CarboMer also offers Polycaprolactone diols and triols and the monomer ε-Caprolactone. European Union (EU) The carbomers may be used in cosmetics and personal care products marketed in Europe according to the general provisions of the Cosmetics Regulation of the European Union. This polymer offers many substantial benefits for formulators and marketers of personal care products. 18% sodium hyaluronate (SH) in treating moderate dry eye. Check out our blog to know more about the Uses of Carbomer, Carbomer Properties, etc. utii ogxwby rsi knsiy hsxf trvhvfd cojh cpy llvdai wieoy